Introduction. The article provides an analysis of publications addressing issues of transfessionalism. When analyzing scientific sources, it was established that there is still no unambiguous interpretation of this concept in psychology, since there is no holistic methodological approach. The purpose consists in the analysis and subsequent systematization and generalization of monographs and scientific articles by domestic and foreign authors devoted to issues of transfessionalism, as well as justification from the point of view of the system-anthropological approach of the concept of transfessionalism. Methods. The methods of research include analysis, systematization and generalization of literature on the problem of research. Results. A literature review revealed that there is currently no clear understanding of the term transfessionalism. This concept is often used as a synonym for the concept of transprofessionalism. Furthermore, the scientific publications we analyzed do not currently describe methodological approaches that clarify the concept of transfessionalism. Therefore, we substantiated the systematic-anthropological approach as one of the promising methodological approaches to understanding transfessionalism in psychology. Conclusion. Based on the analysis of psychological literature, it was concluded that there is currently not enough research that addresses the issue of   transfessionalism development in psychological science. The conducted analysis of psychological literature allowed us to define the essence of the term transfessionalism and substantiate the possibilities of explaining transfessionalism from a systematic-anthropological perspective.